Organic and Biomolecular 新利手机客户端Chemistry (OBC)is delighted to announce a high-profile web themed issue on当代合成化学在药物发现中的应用新利手机客户端.The guest editors for this issue are Professor Angela Russell (University of Oxford,UK),Professor Douglas E.Frantz (The University of Texas at San Antonio,USA),Dr Matthew Duncton (Rigel,San Francisco,USA),Graham Wyne博士（牛津大学，英国）和Shane Krska博士（默克，Boston,USA).
提交截止日期：2016年4月30日
如果你有兴趣参与这个问题，please emailOBC:obc-rsc@rsc.org
Manuscripts can be submitted using the Royal Society of 新利手机客户端Chemistry's在线文章提交服务.Please clearly state that the manuscript is submitted for the themed issue on当代合成化学在药物发现中的应用新利手机客户端.
The level of quality of this issue will be high,所有的手稿都要经过期刊正常的同行评审。Guidelines are available atrsc.li/1K0EgYxandrsc.li/1OoQWQh
Scope of the issue
本课题旨在论证合成化学在药物发现中的重要性。新利手机客户端Specifically it will highlight how synthetic methods can be used to address hurdles currently being faced in modern medicinal 新利手机客户端chemistry.Areas falling within the scope of the issue include:
•CH功能化，including late-stage CH-functionalization & CH-functionalization via biomimetic catalysis
• Fluorination 新利手机客户端chemistry,包括后期氟化，CF3,SCF3和科幻小说5新利手机客户端
• Asymmetric 新利手机客户端chemistry,including use of organocatalytic methods
•具有增强三维特性的化合物的合成（包括交叉耦合和其他金属催化反应，particularly in relation to sp3功能化)
• Modern heterocyclic 新利手机客户端chemistry including synthesis of novel heterocycles,highly-decorated heterocycles & synthesis/use of small heterocyclic groups (e.g.oxetanes,azetidines,etc.)
• Modern synthetic techniques,包括流动化学，新利手机客户端automated synthesis,高通量合成，microwave-assisted 新利手机客户端chemistry,多组分反应与可持续化学新利手机客户端
•天然产物的合成/改性，或天然产物类化合物（以多样性为导向的合成）
• Synthesis utilizing enzymatic 新利手机客户端chemistry and its use in drug discovery
•新试剂/反应在药物发现中的应用
All submissions should clearly show/explain what challenge within drug discovery is being addressed by the presented work.Articles covering general organic synthesis without this connection are not suitable for this issue.
Inclusion of biological data is not a requirement for submission but you are welcome to include any such data that you feel supports your article.Please note that the main focus of the manuscript should be on the organic synthesis and not the medicinal 新利手机客户端chemistry.
To view recent articles or find out more aboutOBC,please visit the journal's homepage:
Organic & Biomolecular 新利手机客户端Chemistry–Rapid publication of high quality organic 新利手机客户端chemistry research
