We atLab on a Chipare very pleased to announce our newest Editorial Board member –Professor Aaron Wheeler。惠勒教授的主任Wheeler Microfluidics Laboratory在多伦多大学。下面,他解释了他是如何进入微流体,该领域面临的挑战,以及为什么他想成为一个曲棍球迷...
1.请告诉我们一个关于你的研究背景不大。
我做了我的博士在化学新利手机客户端与斯坦福大学的理查德“迪克”扎尔工作。我计划工作就与毛细管电泳的项目,但我开始后不久,迪克把我介绍给谁在微流体的“新”领域工作的博士后。几趟洁净室以后,我就迷上了,花了我的时间在斯坦福大学开发的微流体方法来分析单个单元格的内容。在完成博士学位后,我去工作的加州大学洛杉矶分校,在那里我学到了俗称为“数字微流体”或“电润湿的电介质(EWOD)”的技术与罗宾Garrell博士后。罗宾把我介绍给昌金“CJ”金乔噜了,我花了两年时间有一个爆炸的三个实验室之间来回跳跃,开发微流体和质谱之间的接口。(注意学生 - 做博士后这是你可以有一个科学家最有趣的。)然后我就开始了我的职业生涯是在多伦多大学的助理教授,现在我花了我的大部分时间躲在从我的同事们如此我可以用我对他们在实验室中具有乐趣的学生交谈。
2.第一次拿到你感兴趣的实验室在芯片技术作为一个研究领域是什么?
如mentioned previously, a postdoc in my Ph.D. lab, Keisuke Morishima (now a professor at Osaka University), introduced me to microfluidics. The rest, as they say, is history.
3. What do you think the most significant advance in LOC technology has been in the last 5 years?
It is difficult to choose – there have been so many exciting advances. One that sticks out is the方法由穆罕默德碳粉和他的同事为异构悬浮液中提取稀有细胞发育。当我与科学家在实验室上的单芯片社区外说话,这是最经常出现的话题。
4. What do you think is the biggest challenge facing lab on a chip researchers at the moment?
我们的现场继续与新的技术出来的“微流控专家”的实验室,并为最终用户手中的翻译奋斗。
5.你会给年轻的研究人员有什么建议刚刚开始自己的职业生涯?
投机取巧!学术科学家们需要写未来(即赠款)的非常详细的预测。良好的基金申请当然是一个重要的技巧,但我鼓励年轻的研究人员不被愚弄,以为科学会按照剧本!新利手机客户端最初的假设往往是错误(或实验探索它们变成是枯燥),但很有意思的现象比比皆是。睁大你的眼睛,并准备开拓新的和意外的意见。
6.如果你不是一个科学家,你会怎么做?
Hmm. I think I would try to be a part of the US National Public Radio show,RadioLab。If you are not a listener, check it out. I am a huge fan.
7. If you could meet anyone from history, who would it be and why?
Difficult question. I think I will go with Charles Darwin. (True story: I once was thrown out of Westminster Abbey by a large priest with a deep, booming voice for trying to make a charcoal rubbing of Darwin’s gravestone.) Darwin was obviously a source of important, transformative ideas, but he was interested in problems big and small. Apparently, he had a great passion for earthworms (!), going as far as to evaluate their behaviour over several decades by sprinkling markers on the ground to measure worm-driven soil turnover rates. I imagine that with some coaxing, a conversation with Mr. Darwin would cover almost any topic under the sun (or under the soil, as the case may be).
8.什么是你最喜欢的球队?
我在北卡罗莱纳州,在那里大学篮球几乎是一个宗教的国家长大。(真实的故事:有一天上六年级,媒体推车电视机被轧成所有的教室,我们花了一整天看NCAA大学篮球联赛,而不是学习什么,我们都应该做的分数或)所以,我(和我)北卡罗莱纳州(UNC)大学的粉丝 - 在我的成长期,那支球队特色的迈克尔·乔丹。(也许你已经听说过他吗?)自从来到加拿大,我试图成为一个曲棍球风扇。我想是多伦多枫叶队的球迷......但它是非常容易成为一个风扇,如果你的团队实际上赢得一些比赛。
We welcome Professor Wheeler’s expertise to the Board, and look forward to working with him over the coming months.
惠勒教授最近Lab on a Chippapers include:
数字微流体点胶试剂和细胞培养虚拟微孔
欧文A. Eydelnant,Uvaraj Uddayasankar,冰峪“贝蒂”李,孟闻辽,亚伦惠勒R.
Lab Chip, 2012,12, 750-757
DOI:10.1039 / C2LC21004E
对于复用的基于细胞的凋亡试验,一种数字微流体方法
Dario Bogojevic, M. Dean Chamberlain, Irena Barbulovic-Nad and Aaron R. Wheeler
Lab Chip, 2012,12, 627-634
DOI:10.1039 / C2LC20893H
A digital microfluidic method for dried blood spot analysis
Mais J. Jebrail, Hao Yang, Jared M. Mudrik, Nelson M. Lafrenière, Christine McRoberts, Osama Y. Al-Dirbashi, Lawrence Fisher, Pranesh Chakraborty and Aaron R. Wheeler
Lab Chip, 2011,11, 3218-3224
DOI: 10.1039 / C1LC20524B