芯片博客上的实验室 网址://www.xcmww.com/lc 清华大学,2019年5月23日15:01:16+0000 恩努斯 每小时 1 https://wordpress.org/?V= 4.9 通过更便宜的“生命之书” //www.xcmww.com/lc/2019/05/22/through-a-bellower-book-of-life网站/ //www.xcmww.com/lc/2019/05/22/through-a-bellower-book-of-life/回复 结婚,2019年5月22日10:47:04+0000 Burcu Gumuscu 热门文章 DLD阵列 DNA分离 DNA测序 样品制备 //www.xcmww.com/lc/?P=8403 绘制人类基因组计划是世界上最大的科学合作之一。在1000名科学家的努力和30亿美元的预算下,完成“生命之书”的全基因组测序花费了10多年时间。这个庞大的项目完成20年后,现在是可能的[…] <p>绘制人类基因组计划是世界上最大的科学合作之一。Completing the full genome sequencing for "<strong>the book of life</strong>" took more than 10 years with the efforts of 1000's scientists and a budget of $3 billion.这个庞大的项目完成20年后,由于更先进的测序工具,现在可以在8天内以1000美元左右的价格完成一个完整的人类基因组测序。由于基因组测序领域已被更多的应用所接受,因此今天仍有必要进一步改进基因组测序工具,包括法医学,疾病建模与识别,以及个性化药物(例如,识别导致药物在一个病人身上起作用但在另一个病人身上不起作用的基因。<p><p>initial sequence technologies depended on standard dna electrical technologies such as slab gels and毛细血管,一次只能制备少量样品。在人类基因组计划期间,<strong>样本制备限制是增加成本和处理时间的主要原因。在过去的几十年中,许多工作都致力于改进样品制备技术。作为第一步,电泳技术已经过优化,以提高样品吞吐量。更小的,以及功能平台。传统的DNA分离凝胶,几十年来一直是金本位,已经被微加工后阵列和纳米级确定性横向位移阵列所取代。<p>IBM T.J.的研究人员最近展示了纳米级确定性横向位移阵列的一个很好的例子。纽约西奈山沃森研究中心和伊坎医学院,美国。在这项工作中,研究人员将DNA分为100-10000个碱基对,大小选择分辨率为200个碱基对。为了实现这一目标,在硅片上制作了四种不同的微芯片结构,其中阵列和纳米柱的尺寸针对每种配置进行了调整,以获得所选范围的DNA片段的最佳分离性能。每种配置都包含几个单独的阵列,以便在一个芯片中进行独立运行。不是施加电场,研究人员用压力驱动力把碎片分开。该策略尤其适用于在不受缓冲条件影响的情况下分离非带电物种(例如,离子强度)。<p><table class=“AlignCenter”style=“width:100%;border collapse:collapse;border color:ebf562;background color:f9fac5;border style:dashd”border=“1”><tbody><tr><td style=“width:100%”><strong>the separation mechanism</strong>in the nanum scale deterministic lateral displacement array is simple:if the size of a dna fragment大于支柱的直径,碎片以大角度偏向收集墙,也称为“bump mode”(碰撞模式)。如果DNA片段的大小小于柱子的直径,碎片以名义上为零的角度移动,称为“之字形”模式。在这样一个系统中,DNA片段的扩散导致了中间的迁移角,称为“部分碰撞模式”。由于不同模式的存在,不同大小的DNA片段可以在阵列中分离,因为片段将遵循不同的轨迹。图1总结了分离机制,并给出了纳米级确定性侧向位移阵列的轮廓。<td><tr><tbody><table><p>in the nanum scale Deterministic侧向位移阵列,间隙尺寸仅从微尺度调整到纳米尺度,如果不使用任何其他能改变DNA扩散行为的分子,离子强度(改变有效间隙距离)。在这样的环境下,the researchers identified,第一次<strong>不同碎片长度的流速相关性。主要是在不同的DNA片段的给定大小范围内,改变流速会导致凹凸模式和之字形模式之间的转换:缓慢的速度会导致部分凹凸模式,而高速则会导致所有DNA片段的折叠成之字形。纳米确定性横向位移阵列也可作为DNA片段回收率75%和3倍浓度增强的纯化工具。该工具可以有效地用于准备下一代序列库,芯片内DNA鉴定,以及循环DNA表征应用程序。<p><p><p><div id=“attachment_”style=“width:470px”class=“wp caption aligncenter”><a href=“//www.xcmww.com/lc/files/2019/05/picture1.png”><img class=“wp-image-8404”src=“//www.xcmww.com/lc/files/2019/05/picture1.png”alt=“”width=“460”height=“403”srcsset=“//www.xcmww.com/lc/files/2019/05/picture1.png 1281w,图片//www.xcmww.com/lc/files/2019/05/Picture1-300x263.png 300w,//www.xcmww.com/lc/files/2019/05/picture1-768x673.png 768w,//www.xcmww.com/lc/files/2019/05/picture1-1024x897.png 1024w“尺寸=”(最大宽度:460px)100vw,460px“/><a><p class=“wp caption text”>Figure 1.不同流速下的纳米尺度确定性横向位移阵列和DNA分离机制。<p>><div>><p>to download the<strong>full article for free*.<strong>click the link below:<p>><p>><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc01408f/unauth!DivAbstract“>凝胶芯片:连续,利用纳米尺度横向位移进行速度依赖性DNA分离。WunschSung Cheol Kim斯泰西M吉福Yann Astier晁望罗伯特L布鲁斯杰奥蒂卡诉帕特尔伊丽莎白ADuchSimon DawesGustavo Stolovitzky和Joshua T.史密斯,<em><a href=“http://pubs.rsc.org/en/journals/journalissues/lc”!recentarticles&adv“>lab chip.<a>.<em>,2018,Lab on a Chip Articles</p><p><strong>DOI:</strong> 10.1039/c8lc01053f</p><p> </p><p><u>About the Webwriter<a href="//www.xcmww.com/lc/files/2016/11/burcu-150x150.jpg"><img class=" wp-image-6278 alignright" src="//www.xcmww.com/lc/files/2016/11/burcu-150x150.jpg" alt="" width="90" height="90" /></a></u></p><p><a href="https://www.linkedin.com/in/burcu-gumuscu-24748133?trk=hp-identity-name">Burcu Gumuscu</a> is a researcher in Mesoscale Chemical Systems Group at the University of Twente in the Netherlands.她的研究兴趣包括开发用于单细胞蛋白质定量分析的微流体装置,下一代测序,芯片研究的分区器官,and desalination of water on the microscale.</p><p> </p><div class="lightsocial_container"><a 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href=“//www.xcmww.com/lc/files/2019/05/blog pic maria.png”><img class=“AlignRight wp-image-8393”src=“//www.xcmww.com/lc/files/2019/05/blog-pic-maria-231x300.png”alt=“”width=“147”height=“191”srcset=“//www.xcmww.com/lc/files/2019/05/blog-pic-maria-231x300.png 231W,//www.xcmww.com/lc/files/2019/05/blog-pic-maria.png 374w“尺寸=”(最大宽度:147px)100vw,147px“/></a><p><p>This Topic and Exciting Collection is collated by thought leader Dave Weitz and the<em>lab on a chip em>editional board.该集合是由思想领袖Dave Weitz在<a href=“http://rsc.li/weitz edition”>Perspective on single cell sequencing<a>中介绍的,在两篇社论中,一个在“<a href=“http://rsc.li/indrops drop seq”>indrops and drop seq<a>”by allon klein and evan macosko and one on”<a href=“https://pubs.rsc.org/en/content/articlelanding/2017/lc/c7lc90095c!divabstract“>an engineer and business person's perspective</a>”by businesser and engineer mark gilligan.<p><p><strong>read the full collection at:<strong><a href=“http://rsc.li/drop sc seq”>http://rsc.li/drop sc seq.<a><p>below is a selection of content highlights featured in the collection.<strong>in addition,所有论文在31<sup>st<sup>may*.<strong><p><strong>perspective<strong><p><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc01239c!DivAbstract“><strong>Droplet-based single cell rnaseq tools:a practical guide.<strong><a><p>Robert Salomon,大卫·加莱戈·奥尔特加,<em>等人</em><p><p><strong>critical review<strong><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2017/lc/c7lc00241f!DivAbstract“><strong>在干草堆中发现螺旋:核酸细胞术with droplet microfluidics.<strong>><a>><p>iain c.克拉克和亚当R。abate<p><p><strong>paper<strong><p><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c9lc00084d!divabstract“><strong>高通量基因表达谱分析酵母菌落与微凝胶培养drop seq.<strong><a><p>leqian liu,亚当河减弱,<em>等人</em><p><p><strong>paper<strong><p><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c9lc00014c!DivAbstract“><strong>Simplified Drop-Seq Workflow with minimized bead loss using a bead capture and processing microfluidic chip.<strong>><a>><p>Marjan Bio_anin,Bart Deplancke<em>et al</em><p><em>lab on a chip</em>is the leading journal publishing significant and original work related to miniaturisation,在微观和纳米尺度上,多学科读者对期刊影响系数为5.995**感兴趣。《华尔街日报》的主编是亚伯拉罕(Abe)Lee(加利福尼亚大学,Irvine) who is supported by our team of <a href="http://www.rsc.org/journals-books-databases/about-journals/lab-on-a-chip/editorial-board-members/#LC">Associate Editors</a> (Yoon-Kyoung Cho,Petra DittrichHang Lu简华沁Manabu TokeshiJoel Voldman and Aaron Wheeler).</p><p>We hope you enjoy reading the papers within this Thematic Collection and we welcome future submissions on droplet-based single-cell sequencing.</p><p><a href="//www.xcmww.com/lc/2019/03/19/pioneers-of-miniaturization-lectureship-2019-open-for-nominations/?doing_wp_cron=1555576730.7723948955535888671875">Dolomite/<em>Lab on a Chip</em> Pioneers of Miniaturization Lectureship</a>–<strong>deadline approaching-nominate a colleague now!</strong></p><p><a href="//www.xcmww.com/lc/2019/01/31/organ-on-a-chip-systems-translating-concept-into-practice-thematic-collection/">Organ-on a-chip systems- translating concept into practice thematic collection</a> –<strong>Submit now</strong></p><p><a href="https://pubs.rsc.org/en/journals/articlecollectionlanding?themeid=3387ee75-5a44-4ea8-9f69-42b9ad053de5&journalname">Organ-,body- and disease-on-a-chip thematic collection</a> –<strong>Read now</strong></p><p><a href="http://rsc.li/liquid-biopsy">Personalised medicine:liquid biopsy</a>–<strong>Read now</strong></p><p><em><a href="//www.xcmww.com/lc/2017/05/02/emerging-investigator-series-for-lab-on-a-chip/">Lab on a Chip Emerging Investigator Series<strong>–</strong></a></em><strong> Apply now</strong></p><div class="lightsocial_container"><a class="lightsocial_a" 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src="//www.xcmww.com/lc/wp-content/plugins/light-social/google_buzz.png" alt="Google Buzz (aka.google reader)“title=”google buzz(aka.google reader)“/>a>->div> //www.xcmww.com/lc/2019/05/03/lab-on-a-chip-thematic-collection-on-droplet-based-single-cell-sequence/feed/ 0 个性化药液活检芯片专题收集实验室 //www.xcmww.com/lc/2019/05/03/lab-on-a-chip-thematic-collection-on-personalised-medicine-liquid-biophy/ //www.xcmww.com/lc/2019/05/03/lab-on-a-chip-thematic-collection-on-personalised-medicine-liquid-biopsy/回复 周五,2019年5月3日09:25:54+0000 Kate Bandoo出版助理 未分类 洛克 //www.xcmww.com/lc/?P=8395 芯片实验室很高兴与您分享我们关于个性化药液活检的专题收集。这一系列的论文和评论集中在技术进步和液体活检技术的高影响应用之间的接口。本系列由思想领袖Mehmet Toner和Stefanie Jeffrey以及实验室在一个[…]上整理。 <p><em>芯片实验室很高兴与您分享我们关于个性化药液活检的专题收集。<strong>><p>This collection of papers and reviews focusses on the interface between the technological advancements and high impact applications of liquid biopsy technologies.本系列由思想领袖Mehmet Toner和Stefanie Jeffrey以及芯片上的<em>实验室整理,并由思想领袖在<a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc90117a”上的社论中介绍。divabstract“>液体活检:癌症血液探测的视角</a><a href=“//www.xcmww.com/lc/files/2019/05/blog pic maria.png”><img class=“AlignRight wp-image-8393”src=“//www.xcmww.com/lc/files/2019/05/blog-pic-maria-231x300.png”alt=“”width=“177”height=“230”srcsset=“//www.xcmww.com/lc/files/2019/05/blog-pic-maria-231X300,PNG//www.xcmww.com/lc/files/2019/05/blog-pic-maria.png 374w“尺寸=”(最大宽度:177px)100vw,177px“/>.<a><p><p><strong>read the full collection at:<strong><a href=“http://rsc.li/liquid biopsy”><strong>http://rsc.li/liquid biopsy=<strong><a><p>below is a selection of content highlights featured in the collection.<strong>in addition,所有论文在31<sup>st<sup>may*<strong><p><strong>tutorial review<strong><p><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc00684a!DivAbstract“><strong>癌症诊断:从肿瘤到液体活检和超越Chwee Teck Lim<em>等人</em><p><p><strong>critical review<strong><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2018/lc/c8lc00100f!DivAbstract“><strong>循环肿瘤DNA和液体活检:机会,挑战,以及检测技术的最新进展Nam Trung Nguyen先生,穆罕默德J。a.Shiddiky等divabstract“><strong>动态CTC表型在转移性前列腺癌模型中的可视性</strong><a><a href=“https://pubs.rsc.org/en/content/ArticleLanding/2018/lc/c8lc00310f!DivAbstract“><strong>ized using magnetic ranking cytometry.<strong><a>><p>Leyla Kermanshah,莎娜O.Kelley<em>等人</em><p><p><strong>纸张</strong><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc01399c!DivAbstract“><strong>an Ultrasensity test for profiling circular tumor dna using integrated comprehensive droplet digital detection.<strong><a>><p>chen yin ou,蒂莫西J亚伯兰赵伟安等DivAbstract“><strong>通过组合多属性分离和微流体浓度在罕见癌细胞中进行无肿瘤标记富集和直接突变检测teruo fujii<em>等人</em><p><p><strong>纸张</strong><p><a href=“https://pubs.rsc.org/en/content/articlelanding/2019/lc/c8lc01185k!DivAbstract“><strong>尿液液体活检:来自前列腺癌患者的尿液EVS中的非侵入性和敏感性AR-V7检测Hong Koo Hayoon kyoung cho<em>et al</em>is the leading journal publishing significant and original work related to miniaturisation,p><p><p><em>lab on a chip.<em>is the leading journal publishing significant and original work related to miniaturisation,在微观和纳米尺度上,多学科读者对期刊影响系数为5.995**感兴趣。《华尔街日报》的主编是亚伯拉罕(Abe)Lee(加利福尼亚大学,Irvine) who is supported by our team of <a href="http://www.rsc.org/journals-books-databases/about-journals/lab-on-a-chip/editorial-board-members/#LC">Associate Editors</a> (Yoon-Kyoung Cho,Petra DittrichHang Lu简华沁Manabu TokeshiJoel Voldman and Aaron Wheeler).</p><p>We hope you enjoy reading the papers within this Thematic Collection!</p><p>Keep up to date with <a href="https://www.rsc.org/journals-books-databases/about-journals/lab-on-a-chip/"><em>Lab on a Chip</em></a> throughout the year by <a href="http://click.rsc.org/rsps/m/uZ4RAb9ie2CfZBgQaw_NQl0dFlT6W-EtuvHgO7AXAeM">signing up</a> for free table of contents alerts and monthly e-newsletters.</p><p><a 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alt="Google Buzz (aka.google reader)“title=”google buzz(aka.google reader)“/>a>->div> //www.xcmww.com/lc/2019/05/03/lab-on-a-chip-thematic-collection-on-personalised-medicine-liquid-biophy/feed/ 0 新研究者系列——马修·奥迪jk //www.xcmww.com/lc/2019/05/02/emerging-researcher-series-mathieu-odijk/ //www.xcmww.com/lc/2019/05/02/Emerging Investor Series Mathieu Odijk/回复 清华大学,2019年5月2日09:36:26+0000 Courtney Rowan开发编辑 新兴研究者 //www.xcmww.com/lc/?P=8384 Mathieu Odijk是特温特大学的副教授,他在化学分析的微和纳米设备上有自己的研究主题。他因在药物筛选和蛋白质组学应用的电化学微反应器方面的工作,在阿尔伯特·范登伯格的指导下,从特文特大学获得了电气工程博士学位。 <p><span style=“color:000000”><a style=“color:000000”href=“//www.xcmww.com/lc/files/2019/05/mathieu odjik.png”><img class=“wp-image-8385 AlignLeft”src=“//www.xcmww.com/lc/files/2019/05/mathieu-odjik.png”alt=“”width=“359”height=“269”srcsset=“//www.xcmww.com/lc/files/2019/05/mathieu-odjik.png 1431w,//www.xcmww.com/lc/files/2019/05/mathieu-odjik-300x225.png 300w,//www.xcmww.com/lc/files/2019/05/mathieu-odjik-768x576.png 768w,//www.xcmww.com/lc/files/2019/05/mathieu-odjik-1024x768.png 1024w“尺寸=”(最大宽度:359px)100vw,359px“/><a><span><p><a href=“https://people.utwente.nl/m.odijk”>mathieu odijk<a>is an associate professor at the university of twente running his own research theme on<a href=“https://www.utwente.nl/en/eemcs/bios/research/chemicallanalysis/”>micro-and nanovices for chemical analysis<a>。2011年,他在阿尔伯特·范登伯格(Albert van den Berg)的指导下获得了特文特大学(University of Twente)的电气工程博士学位,负责电化学微反应器的药物筛选和蛋白质组学应用。通过对EPFL洛桑(2012年)的各种研究访问,他扩大了自己的研究范围。哈佛Wyss学院(2013年)和MIT(2014年)。<p><p>The common aim of his research is to design novel devices to measure chemical quantities,在应用程序中推进边界以探索未知领域。Often,这关系到更快,or better spatially resolved measurements at lower concentrations in small volumes.微和纳米制造技术用于增强电化学,光学或质谱读数。最终目标是创造新的,yet robust tools for routine use in the lab or point-of-care applications.</p><p>Read Mathieu Odijk 's Emerging Investigator article "<a href="https://pubs.rsc.org/en/content/articlepdf/2019/lc/c8lc01137k">A miniaturized push–pull-perfusion probe for few-second sampling of neurotransmitters in the mouse brain</a>" and find out more about him in the interview below:</p><p><strong>How has your research evolved from your first article to your most recent Emerging Investigator article?</strong></p><p>I have nice memories about my first paper,因为它也被提交到芯片实验室,并立即接受,没有修改(只有一个小问题,从1个裁判员的)。第一篇论文的主题是研究药物代谢研究中氧化转化的电化学微反应器的设计。我们在这个问题上取得了很大的成功,现在还将其延伸到电化学氧化蛋白裂解的研究方向,以及使用例如光谱电化学方法。<p>先进的洁净室制造,以及分析化学。新利手机客户端这些成分也构成了我自己研究小组(用于化学分析的微型和纳米设备)重点领域的一个关键组成部分。<p><p><strong>What aspect of your work are your most engined about at the moment?<strong><p><p>it is my aim to push the bounders of existing analytical tools with respect to limit detection,空间或时间分辨率,或者使用高通量技术增加重复次数。我对最近的一篇演示小型推拉灌注探头的论文感到非常兴奋,因为它确实比商用探针提高了至少1个数量级的空间和时间分辨率。像这样的,这是一个很好的展示微流体可以达到什么样的效果。<p><strong>在您看来,在这个研究领域,最重要的问题是什么?.<strong><p><p>I think it is really important to focus on the final application,找到好的合作伙伴。如果我以这个推拉式灌注探头为例,这项研究起源于与神经科学家的讨论,他们抱怨现有的微透析探头缺乏时间信息。然而,许多描述微流体通道探针的论文仅证明了体外结果。正如我们在项目中发现的那样,在体内弥合鸿沟当然不是件小事。如果你坚持进行体外实验的话,它需要在技术领域做出让步,而这一点你将无法解决。<p>more generally I believe that the field has de熟;芯片技术实验室已经成为实现更高目标的一种手段。在这种情况下,这个更高的目标是更详细地研究大脑中的神经化学过程。然而,我认为这个项目也清楚地表明了在工程学中可以有很多科学。新利手机客户端在这种情况下,我们必须克服微加工的挑战,流体动力学,大众运输,蛋白质化学,新利手机客户端和吸附动力学。<p><strong>你觉得你的研究最具挑战性的是什么?我发现真正有趣的是我的研究在自然界中是非常多学科的,跨越传统界限,如“化学”,新利手机客户端“物理学”,或“生物学”。然而,这也构成了一个挑战,因为如果你正在探索一个新的研究领域,很容易形成一个盲点。再次,我想强调与这些领域的专家进行良好合作的重要性,以防止在早期阶段出现故障。<p><strong>in which negoing conferences or events may our readers meet you?<strong>><p>that is easy:i always try to attain microtas.<p>><strong>how do you spend your spare time?我是两个小孩的父亲,年龄1岁和4岁。如果他们给我留下一些空闲时间(和精力),我喜欢做木工,骑脚踏车兜风,室内攀岩。我也很喜欢户外溜冰,但不幸的是,全球变暖干扰了荷兰溜冰的可能天数。如果你不是科学家,你会选择哪个职业?我一直想成为一名发明家,以老师为亚军。我想成为一名科学家实际上与儿时的梦想非常接近。任何其他职业都应该让我能够创造新事物,或教育其他人(或两者兼而有之)。<p><strong>Can you share one pice of career relevant advice or withness with other early career sciests?在我的任期轨迹中的各个点上,我感到表演的压力。这可能会带来压力,而且肯定会适得其反。试着不断地看到/发现科学的乐趣,新利手机客户端例如让你的博士生和你分享他们在实验室的发现时刻。其余的都不那么重要。<p><div class=“lightsocial_container”><a class=“lightsocial_a”href=“http://digg.com/submit”?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f05%2f02%2fEmerging Investor Series Mathieu Odijk%2f&title=Emerging+Investor+Series+%e2%80%93+Mathieu+Odijk“><img class=“light social\u img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/digg.png”alt=“digg this”title=“digg”/><<a class=“lightsocial\u a”href=“http://www.reddit.com/submit?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f05%2f02%2fEmerging Investor Series Mathieu Odijk%2f&title=Emerging+Investor+Series+%e2%80%93+Mathieu+Odijk“><img class=“light social\u img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/reddit.png”alt=“reddit this”title=“reddit”/>=<a>>//www.stumbleupon.com/submit?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f05%2f02%2fEmerging Investor Series Mathieu 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AlignLeft”src=“//www.xcmww.com/lc/files/2019/04/hw-hou.jpg”alt=“”width=“307”height=“288”srcset=“//www.xcmww.com/lc/files/2019/04/hw-hou.jpg 439w,//www.xcmww.com/lc/files/2019/04/hw-hou-300x281.jpg 300w“尺寸=”(最大宽度:307px)100vw,307px“/>.<a>><p><p style=“text-align:left”>dr.<a href=“http://www.hwhoulab.com”>han wei hou目前是机械与航空航天工程学院和李光强医学院(LKCmedicine)的助理教授,南洋理工大学新加坡。2008年和2012年,他获得新加坡国立大学生物医学工程学士(一等荣誉)和博士学位。分别。毕业后,他在麻省理工学院(MIT)接受博士后培训,and subsequently joined LKCMedicine at NTU as the inaugural LKCMedicine Postdoctoral Fellow in 2014.</p><p style="text-align: left">Dr.侯先生有30多篇同行评审的科学出版物,他的作品被刊登在《网络科学》(ScienceDaily,新利手机客户端科学家,癌孔和基因组网)医疗保健(新闻医学)以及科技杂志(Gizmag,Nanowerk)他曾获得多项科学奖,包括新加坡麻省理工学院研究与技术联盟(SMART)研究生奖学金(2009年)。第六届世界生物力学大会青年研究员奖(2010年)和LKCmedicine博士后奖学金(2014年)。<p><p><p><p style=“text-align:left”>his current research focus on developing novel microfluidics point of care testing,以及用于转化型糖尿病和心血管疾病研究的仿生片上器官技术。(研究组网站:<a href=“http://www.hwhoulab.com”>www.hwhoulab.com<a>)<p><p>read Han Wei Hou's Emerging Investor Article“<strong><a href=“https://pubs.rsc.org/en/content/Articlepdf/2019/lc/c9lc00250b”>集成惯性阻抗细胞术,用于快速无标签白细胞分离和中性粒细胞外陷阱分析(nets)<a><strong>“and find out more about him in the interview below:<p><p><strong>your recent emerging investigator series paper focus on integrated imilsion impedance cytometry for rapid label free blackcell isolation and profiling of neutrophil extracellular traps(nets).你的研究是如何从你的第一篇文章发展到最新的研究者文章的?当我还是本科生的时候,我的第一篇文章是关于使用微流体研究癌症生物力学的。从那时起,I worked on other blood-related diseases such as malaria,脓毒症和糖尿病,逐渐地,人们对微流体的研究越来越感兴趣,这使得对代谢性疾病的宿主炎症和免疫反应的研究成为可能。无论疾病类型如何,我们的核心理念是开发集成的无标签细胞分类和生物传感方法,使其价格低廉,快速且易于转化为临床应用。在我看来,这项工作是所有方面的一个很好的组合。<p><p><strong>你目前最兴奋的工作是什么方面?<strong><p><p>with this paper,我们现在可以用一滴血在几分钟内通过一次单步骤的用户操作来评估免疫健康。我们相信这部作品具有巨大的翻译潜力,我们正在积极寻找新的合作者来测试其他免疫功能紊乱的疾病。<p><strong>在您看来,从创建设备到将其用于糖尿病的护理点测试,下一步是什么?在这个研究领域,最重要的问题是什么?通过本工作和我们集团最近的其他工作,我们发现糖尿病白细胞具有明显的介电差异,可用于免疫健康风险分层。接下来要问的几个重要问题是为什么它们不同,以及我们如何进一步开发我们的技术/分析以提高预测能力。<p><strong>您认为您的研究最具挑战性的是什么?我们的工作是高度跨学科的,最具挑战性的方面是找到合适的人(合作者,学生等)提出正确的科学问题(不太基础科学,新利手机客户端不要太临床化,也不要太工程化)!<p><p><strong>in which negoing conferences or events may our readers meet you?<strong><p><a href=“https://cbmsociety.org/conferences/microtas2019/”>microtas 2019<a>(巴塞尔)and<a href=“https://selectbiosciences.com/conferences/index.aspx”?co新利手机客户端nf=mfasia2019“>Microfluidics&Organic-on-a-chip Asia Conference 2019</a>(Tokyo)<p><strong>How do you spend your spare time?<p>家庭时间!现在我喜欢和我18个月大的女儿汉娜在一起,他从不取笑我,也从不让我疲劳。如果时间允许,我也会去看我们的深夜脱口秀!如果你不是科学家,你会选择哪个职业?<p>艰难的选择!我在做乐高/玩具设计师和飞行员之间很纠结。<p><strong>你能和其他早期职业科学家分享一条与职业相关的建议或智慧吗?<strong><p><p>与研究学科之外的人交谈。如果有必要,请学习解除束缚,因为科学和技术进步如此之快。<p><p><p><p><p><p新利手机客户端><div class=“lightsocial_container”><a class=“lightsocial_a”href=“http://digg.com/submit”?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f04%2f24%2fEmerging Investor Series Han Wei Hou%2f&title=Emerging+Investor+Series+%e2%80%93+Han+Wei+Hou“><img class=“light social\u img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/digg.png”alt=“digg this”title=“digg”/>=<a class=“lightsocial\u a”href=“http://www.reddiT.COM/提交?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f04%2f24%2fEmerging Investor Series Han Wei Hou%2f&title=Emerging+Investor+Series+%e2%80%93+Han+Wei+Hou“><img class=“light social\u img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/reddit.png”alt=“reddit this”title=“reddit”/><a class=“lightsocial\u a”href=“http://www.stumbleupon.com/submit?提交?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f04%2f24%2fEmerging Investor Series Han Wei Hou%2f&title=Emerging+Investor+Series+%e2%80%93+Han+Wei+Hou“><img class=“light social”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/Stumbleupon.png”alt=“Stumble 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social_img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/google_buzz.png”alt=“google buzz(aka)。google reader)“title=”google buzz(aka.google reader)“/>a>->div> //www.xcmww.com/lc/2019/04/24/emerging-researcher-series-han-wei-hou/feed/ 0 改善天然气提取工艺的微流体 //www.xcmww.com/lc/2019/04/23/microfluidics-for-improvement-natural-gas-extraction-process/微流体技术/ //www.xcmww.com/lc/2019/04/23/microfluidics for improving natural gas extraction process/回复 星期二,2019年4月23日13:44:25+0000 Burcu Gumuscu 热门文章 //www.xcmww.com/lc/?P=8304 页岩是一种含粉土的细粒岩石,粘土,矿物颗粒,以及从米到纳米尺度的孔隙。页岩中有机质含量高,用于天然气开采。对页岩储层进行机械刺激,在孔隙中形成渗透性。首选的刺激方法称为水力法。 <p><p><div id=“attachment_”style=“width:262px”class=“wp caption alignright”><a href=“//www.xcmww.com/lc/files/2019/03/fig1 ou shale rock.png”><img class=“wp-image-8305”src=“//www.xcmww.com/lc/files/2019/03/fig1 ou shalerock.png”alt=“shele rock”width=“252”height=“303”srcset=“//www.xcmww.com/lc/files/2019/03/fig1 ou shalerock.pnG 66W,//www.xcmww.com/lc/files/2019/03/fig1-shalerock-249x300.png 249w“尺寸=”(最大宽度:252px)100vw,252px“/><a><p class=“wp caption text”>Figure 1.页岩天然气开采。<p><div><p><a href=“https://www.eia.gov/energyexplained/index.php”?page=natural_gas_where“>页岩是一种含粉土的细粒岩石,粘土,矿物颗粒,以及从米到纳米尺度的孔隙。页岩中有机质含量高,用于天然气开采。对页岩储层进行机械刺激,在孔隙中形成渗透性。首选的增产方法是水力压裂。其中,加压流体破裂页岩岩,并使裂缝保持开放状态以进行气体开采(图1)。与现有能源相比,页岩气开采是一个相对较新的过程。由于它是其他消耗性能源的环境友好替代品,它吸引了美国和亚洲越来越多的兴趣,尤其是在21世纪后。另一方面,天然气工业目前正在努力优化利用孔隙空间和分馏物有效提取天然气。在一个新开的页岩储层中,挥发性成分首先从米级蒸发到微米级孔隙,使较重的成分难以进入纳米级的孔隙。提取剩余的成分是充分利用水库的必要条件,但对行业来说,这是一个难以解决的问题。<p><p>.<p>.<p><p>.<p><p>in a recent study published in<em>lab on chip.<em>,<a href=“https://pubs.rsc.org/en/content/articlepdf/2019/lc/c8lc01053f”>david sinton and co-authors.>Review the current state of the technology and example a nano-scale physical model of shale with孔隙。作者还通过光学成像和建立气体蒸发的分析模型,研究了纳米孔中气体生成的动力学。他们首先创建了一个与页岩纳米多孔基质特性相匹配的微芯片模型(例如,主要孔隙尺寸和渗透性(图2)。微芯片模型包含大约5800个通过23000个喉道连接的孔,注入碳氢化合物混合物的地方。在模型中,小孔隙的数量(≤10 nm)设计大于大孔隙的数量(~100 nm),以储存大部分可获取的碳氢化合物。这种孔径分布捕获了连接较大孔隙的纳米级喉道的影响,并与页岩生产有关。高,培养基,并且将low<a href=“https://en.wikipedia.org/wiki/superheating”>superheat<a>应用于填充的微芯片,以通过光学成像研究蒸发的时空动力学。分析模型和实验结果表明,孔中的相变化(液体到蒸汽)在很大程度上独立于相邻孔中的相变化。<p>此项工作支持这样一种假设,即生产速率的快速下降是由于从大连接特征到纳米孔基质的转变所致,随着时间的推移,最小的毛孔中含有较重的部分。作者发现,由于纳米尺度的高温喉道瓶颈,蒸发速度减慢了3000倍。而在低温下,随着轻质组分在大孔中的蒸发,速率进一步降低。即使是直径小于等于10纳米的孔,也能通过严重的选通传输,显著影响较大孔的生产。作者发现这个问题可以通过施加非常低的压力来解决。尽管目前该领域还不可用,水力压裂后期。这一发现似乎为页岩能源加工领域开辟了一条新的道路。<p><div id=“attachment_”style=“width:630px”class=“wp caption aligncenter”><a href=“//www.xcmww.com/lc/files/2019/03/fig2 ou vaporation.png”><img class=“wp-image-8306”src=“//www.xcmww.com/lc/files/2019/03/fig2 ou vaporation.png”alt=“”width=“620“height=”401“srcset=”//www.xcmww.com/lc/files/2019/03/fig2_vaporation.png 1272w,//www.xcmww.com/lc/files/2019/03/fig2-300x194.png 300w,//www.xcmww.com/lc/files/2019/03/fig2-vaporation-768x497.png 768w,//www.xcmww.com/lc/files/2019/03/fig2_vaporation-1024x663.png 1024w“尺寸=”(最大宽度:620px)100vw,620px“/><a><p class=“wp caption text”>Figure 2.页岩的近景,关于蒸发过程的描述,以及微芯片操作的说明。<p>><div>><p>to download the<strong>full article for free*.<strong>click the link below:<p>><p>><a href=“https://pubs.rsc.org/en/content/articlelanding/2018/lc/c8lc01053f/unauth!DivAbstract“>页岩纳米喉道连通模型中的天然气蒸发:多尺度,多组分和多相俊杰中Ali Abedini阿泰娜·谢巴蒂安,Yinuo Zhao哲慧金Farshid Mostowfi and David Sinton<<p><em><a href=“http://pubs.rsc.org/en/journals/journalissues/lc”!recentarticles&adv“>lab chip.<a>.<em>,2018,lab on a chip文章</p><p><strong>doi:<strong>10.1039/c8lc01053f<p><p>*article free to read until 7th may 2019<p><p><u>about the webwriter<a href=“//www.xcmww.com/lc/files/2016/11/burcu-150x150.jpg”><img class=“wp-image-6278 AlignRight”src=“//www.xcmww.com/lc/files/2016/11/burcu-150x150.jpg”alt=“”width=“94”height=“94”/></a></u>><p>><a href=“https://www.linkedin.com/in/burcu-gumuscu-24748133”?trk=hp identity name“>burcu gumuscu<a>是荷兰特温特大学中尺度化学系统组的研究员。她的研究兴趣包括开发用于单细胞蛋白质定量分析的微流体装置,下一代测序,芯片研究的分区器官,在微型天平上对水进行脱盐。<p><p><p><div 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img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/twitter.png”alt=“post on twitter”title=“post on twitter”/>=<a class=“light social\u a”href=“http://www.google.com/buzz/po”圣?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f04%2f23%2改善天然气开采过程的微流体%2f“><img class=“light social”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/google-buzz.png”alt=“google buzz(aka)。google reader)“title=”google buzz(aka.google reader)“/>a>->div> //www.xcmww.com/lc/2019/04/23/microfluidics-for-improvement-natural-gas-extraction-process/feed/ 0 新兴研究者系列——杰西S。珍 //www.xcmww.com/lc/2019/03/25/emerging-research-series-jessie-jeon/ //www.xcmww.com/lc/2019/03/25/emerging research series jessie jeon/回复 周一,2019年3月25日16:40:18+0000 卡林顿先生,编辑助理 新兴研究者 抗生素 新利手机客户端 新兴研究者 工程 新利手机客户端 //www.xcmww.com/lc/?P=8341 博士。杰西斯杰恩接受了她的某人,钐麻省理工学院机械工程博士(2008年,2010,2014)在贝丝以色列女执事医疗中心做研究员,(2014-2015)。她于2015年秋季加入凯斯特学院,担任机械工程系助理教授。[…] <p><a href=“//www.xcmww.com/lc/files/2019/03/jessie-s-jeon.jpg”><img class=“size medium wp-image-8342 AlignLeft”src=“//www.xcmww.com/lc/files/2019/03/jessie-s-jeon-277x300.jpg”alt=“”width=“277”height=“300”srcsset=“//www.xcmww.com/lc/files/2019/03/jessie-s-jeon-277x300.jpg 277W,//www.xcmww.com/lc/files/2019/03/jessie-s-jeon-768x831.jpg 768W,//www.xcmww.com/lc/files/2019/03/jessie-s-jeon-946x1024.jpg 946W,//www.xcmww.com/lc/files/2019/03/jessie-s-jeon.jpg 1512W“尺寸=”(最大宽度:277px)100vw,277px“/><a><span style=“color:008080”><strong><a style=“color:008080”href=“http://jeon.kaist.ac.kr/”>dr.杰西斯杰恩</a><strong><span>Received her sb,钐麻省理工学院机械工程博士(2008年,2010,2014)在贝丝以色列女执事医疗中心做研究员,(2014-2015)。她于2015年秋季加入凯斯特学院,担任机械工程系助理教授。她的研究重点是微流体平台的开发,以及在生物系统研究中的应用。她计划进一步开发微流体系统,重点是流体方面,并扩大其在模拟各种器官疾病系统以及其他生物微环境方面的应用。这样做,她希望将生物医学研究的需求与机械工程原理的知识联系起来。Jeon's Emerging Investor Article“<a href=“https://pubs.rsc.org/en/content/Articlepdf/2019/lc/c8lc01406j”><strong><span style=“color:008080”>on chip hypomic investigation of combinatory抗生素effects by generating正交浓度梯度</span><strong>”<a><span style=“font-family:Georgia,palatino,serif“>并在下面的访谈中了解关于她的更多信息:.<span><p><strong>Your recent emerging investives series paper focus on-chip hypomical investigation of combinational抗生素effects.你的研究是如何从你的第一篇文章发展到最近的这篇文章的?我的小组首先在基于微流体的单一抗生素测试平台上工作,我们可以减少抗生素敏感性测试(AST)所需的时间。当我们进一步了解AST时,我们认识到,近年来对抗生素的研究大多集中在组合抗生素效应的研究上。由于微流体平台能够实现多通道组合,it was quite natural to try a combination of antibiotics in one chip.</p><p><strong>What aspect of your work are you most excited about at the moment?</strong></p><p>Broadly speaking,我很高兴我们可以利用我们的平台来筛选个性化药物。这是使用微流体平台筛选患者特定的治疗。认为我们的技术将有助于提高我们的生活,这无疑激励了我致力于这个主题。<p><strong>在你看来,基于芯片的临床治疗筛查的未来是什么?我相信随着芯片实验室的发展,我们可以使用患者自己的细胞筛选出最理想的治疗策略,and this technology would bring the biggest impact to the society.这包括在治疗方法方面的策略选择以及抗生素或抗癌药物组合治疗的可能性。That is also in line with my answer for the question above that I am very excited for the opportunities in personalized medicine with lab-on-a-chip technology.</p><p><strong>What do you find most challenging about your research?</strong></p><p>As a researcher in an interdisciplinary field,对我来说,找出有意义的生物学和生物医学问题总是很有挑战性的,我可以用我的专业知识来解决这些问题。我认识到与临床医生和生物学家保持密切的关系是非常重要的。我们的读者可能会在哪些即将举行的会议或活动中遇到你?<strong><p><p>i plan to atteed the<span style=“color:008080”><strong><a style=“color:008080”href=“https://www.bmes.org/annuallmeeting19”>2019 Annually Meeting of the Biomedical Engineering Society.<a><strong><span>in coming October.<p><strong>how do you spend your spare time?我喜欢玩各种运动,现在大多是网球,如果可能的话,我也会尽量多和家人一起短途旅行。<p><strong>如果你不是科学家,你会选择哪种职业?当我在大学时,也许我会在军队中服役,因为我短暂地参加了后备军官训练队的计划。<p><strong>can you share one pice of career related advice or with智慧with other early career sciences?当我仍处于需要他人提供大量建议的位置时,我想分享我的想法,如果你不放弃,there will be opportunities to come.</p><div class="lightsocial_container"><a class="lightsocial_a" href="http://digg.com/submit?url=http%3A%2F%2Fwww.xcmww.com%2Flc%2F2019%2F03%2F25%2Femerging-investigator-series-jessie-jeon%2F&title=Emerging+Investigator+Series+-+Jessie+S.+Jeon" ><img 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Collins,麻省理工学院美国<br/>Dino di Carlo教授,University of California,洛杉矶,美国堪萨斯州立大学美国<br/>Daniel Irimia博士,哈佛医学院,United States<br />Dr Séverine Le Gac,特温特大学荷兰<br/>Robert Meagher博士,桑迪亚国家实验室,美国<br/>迈克尔·罗珀教授,佛罗里达州立大学美国<br/>Edmond Young博士,多伦多大学加拿大<<p>We would also like to thank the<em>lab on a chip<em>board and the<em>lab on a chip<em>community for their continued support of the journal,作为作者,评论人和读者。<p>如果你想成为我们期刊的评论人,只需发送电子邮件给我们,地址为:loc-rsc@rsc.org“>loc-rsc@rsc.org”,其中包含您的研究兴趣和最新的简历或R_sum_。您可以在<a href=“http://www.rsc.org/journals books databases/journal authors reviewers/reviewer responsibilities/being reviewer”>our author and reviewer resource centre<a><p><div class=“lightsocial\u container”><a class=“lightsocial\u a”href=“http://digg.com/submit”中找到更多详细信息。url=http%3a%2f%2fbloblog.rsc.org%2flc%2f2019%2f03%2f20%2fbu杰出-评审员-for-lab-on-a-chip-in-2018%2f&title=bu杰出+评审员+for+lab+on+a+chip+in+2018“><img class=“Light社会性\u img”src=“http://blog.rsc.org/lc/wp-conte/plugins/轻-社会/digg.png”alt=“digg 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//www.xcmww.com/lc/2019/03/20/outstanding-reviewers-for-lab-on-a-chip-in-2018/feed/ 0 微型化的先驱讲座2019:公开提名 //www.xcmww.com/lc/2019/03/19/preventors-of-minitalization-dresship-2019-open-for-nominations/ //www.xcmww.com/lc/2019/03/19/preventors-of-minitalization-teacheship-2019-open-for-nominations/回复 星期二,19 Mar 2019 11:28:51 +0000 卡林顿先生,编辑助理 会议 小型化讲座的先驱 //www.xcmww.com/lc/?P=8290 芯片实验室和白云石自豪地赞助了第十四位小型化演讲的先驱,为了表彰和支持未来的发展,对小型系统的理解或发展做出重大贡献的下一代科学家。今年的演讲将在巴塞尔举行的礹塔斯2019年会议上进行。瑞士,收件人收到[…] <p><a href="//www.xcmww.com/lc/files/2019/03/capture3.png"><img class=" wp-image-8300 aligncenter" src="//www.xcmww.com/lc/files/2019/03/capture3-300x116.png" alt="" width="385" height="149" srcset="//www.xcmww.com/lc/files/2019/03/capture3-300x116.png 300w,//www.xcmww.com/lc/files/2019/03/capture3.png 644w“尺寸=”(最大宽度:385px)100vw,385px”/>-<p><p><p><span style=“color:\35;008080“><a style=“color:\\\\\\\\\\\\px”/>>><a><P><P><p><p><p><p><p><p><p><p><p><p><span span stylestylestyle=“style::\\\\\\\\\\\一个为了表彰和支持未来的发展,对小型化系统的理解或发展做出重大贡献的下一代科学家。<p><p>今年的演讲将在巴塞尔的<a href=“https://microtas2019.org/”>祫tas 2019会议上进行。瑞士</a>与接收者一起获得2000美元的奖金。<p><p>The TeachesHip composites of the following elements:<p><ul><li>a prize of US$2000.不会提供任何其他财政捐助</li><li>a certificate recognsing the winner of the sterneship<li><li>the awaredee is required to give a short learning at the 2019礹tas conference<li><ul><p>.<p><strong>qualification criteria</strong><p>to be qualified for the sterneship,候选人必须:<p><ul><li>have completed their phd.<li><li>be activitive pushing an independent research career on minitarized systems.<li><li>be at an early mid career stage of their independent career(typically this will be within 15 years of completing their phd,但是,对于那些中断了职业生涯或走了不同的学习道路的人,将给予适当的考虑。<li><ul><p><strong>提名过程</strong><p>to be considered for the 2019 steacheship,以下内容必须发送给编辑部,说明候选人的成绩以及为什么讲师值得推荐。<li>被提名人必须知道,他/她已经被提名为该讲师。<li>a complete nomination form(includes list of the candidate's relevant publications or recen工作,候选人的科学简历,以及完整的联系方式)不允许来自学生的提名和自我提名。<li><ul><p><strong>选择标准和判断过程</strong><ul><li><strong>提名必须通过电子邮件发送到loc-rsc@rsc.org使用<a href=“http://www.rsc.org/globalassets/05-journals-books-databases/our-journals/lab-on-a-chip/Dolomite ou loc-Promotives-Nomination-Form-2019.pdf“>Dolomite/<em>lab on a chip</em>Promotives of minitalization讲师提名表</a>and a letter of recommendation.<strong><li><li>The decision on the winner of the演讲者将由一个由Dolomite的代表和成员组成的评委小组做出编辑委员会,由芯片上实验室的执行编辑协调,该奖项是为理解或开发微型化系统做出杰出贡献的。这将主要通过他们的前1-3篇论文和/或专利/或商业产品记录的发明来判断。Awards and honorary memberships may also be considered.</li></ul><p><strong>Nomination Deadline: 31 May,2019年</strong><p><p style=“text-align:center”><a href=“https://www.rsc.org/globalassets/05 journals books databases/our journals/lab-on-a-chip/dolomite ou loc-proonents-nomination-form-2019.pdf”><span style=“font-size:12pt”><strong><span style=“color:008080”>下载提名表here</span><strong><a><p><strong>previous winners</strong><p><ul><li><span style=“font-family:乔治亚州,palatino,SERIF“>2018:Sunghoon Kwon教授,首尔国立大学,韩国palatino,SERIF“>2017:Aaron Wheeler教授,多伦多大学加拿大palatino,serif“>2016:Daniel Irimia教授,马萨诸塞州总医院,美国palatino,serif“>2015:迪诺·迪卡洛教授,University of California,洛杉矶,美国palatino,serif“>2014:Sangeeta N.教授。Bhatia,麻省理工学院美国palatino,SERIF“>2013:水池高桥教授,密歇根大学美国palatino,serif“>2012:安德鲁·德米洛教授,ETH Zürich,瑞士palatino,2011年:Ali Khademosseini教授,麻省理工学院美国palatino,2010年:斯蒂芬·奎克教授,斯坦福大学,美国palatino,serif“>2009年:Abe Lee教授,University of California,尔湾美国palatino,2008年:Patrick Doyle博士,麻省理工学院美国palatino,serif“>2007:Manabu Tokeshi博士,名古屋大学,日本palatino,2006年:大卫·毕比博士,威斯康星大学美国属于Blacktrace组,是微流体产品设计和制造领域的世界领先者。我们的系统灵活且模块化,允许用户在生物学中执行广泛的应用程序,新利手机客户端化学,药物发现,食物,化妆品,和学术界。掌握专业知识,我们可以与您讨论您的需求,以确保您为您和您的研究找到正确的系统。<p><em><strong>lab on a chip.<strong><em><p><em><a href=“http://www.rsc.org/journals books databases/about journals/lab-on-a-chip/teacheship_loc“>lab on a chip.<a><em>provides a unique forum for the publication of significant and origina与小型化有关的工作,在微观和纳米尺度上,对多学科读者感兴趣。《华尔街日报》力求在物理技术进步和对广大读者有直接兴趣的高影响力应用程序之间的界面上发表文章。<p><div class=“lightsocial_container”><a class=“lightsocial_a”href=“http://digg.com/submit”?url=http%3a%2f%2fblowww.xcmww.com%2flc%2f2019%2f2019%2f03%2f19%2fofofofofs-of-微型化-讲师希ip-2019-开放-for-提名%2f&title=拓荒者+of+微型化+讲师希ip+2019%3a+开放+for+提名“><img class=“Light社会\img”src=“http://blog.rsc.org/lc/wp-conte/plugins/轻-社会/digg.png.png”alt=“digg本”title=“digg=“digg本”/>/>>>a>160;;<a>>a>>格格格格格格格格格160Class=“lightsocial_a”href=“http://www.reddit.com/submit”?url=http%3a%2f%2fwww.xcmww.com%2flc%2f2019%2f03%2f19%2freaters-of-minitalization-teacheship-2019-open-for-nominations%2f&title=freaters+of+minitalization+teacheship+2019%3a+open+for+nominations“><img class=“light social\u img”src=“//www.xcmww.com/lc/wp-content/plugins/light-social/reddit.png”alt=“reddit this”title=“reddit this”/><<a 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1024w“尺寸=”(最大宽度:277px)100vw,277px“/><a>the<span style=“color:008080”><strong><a style=“color:008080”href=“http://torontommicrofluidics.ca/ooac/”>14 Annuary Ontario-on-a-chip<a><strong><span>Symposium will take place between<strong>16th-17th May 2019<strong>at the<strong>University of Toronto<strong>the Symposium will feature talks from the following keynoTE扬声器:<strong><span style=“color:008080”><a style=“color:008080”href=“http://loskill-lab.com/index.html”>dr.Peter Loskill 008080“><strong><a style=“color:008080”href=“http://www.gao.caltech.edu/”>drWei Gao.<a><strong><span>From Caltech,<strong><span style=“color:008080”>.<span><strong><a href=“http://www.tulane.edu/~mooremj/”><span style=“color:008080”><strong>d<span style=“color:008080”>r.<span>Michael Moore.<strong><span><a>From Tulane University,and;<strong><span style=“color:\\\\\\\\\\\\\\\<stron<stron<stron<strong><<span style<span style=“颜色:\\\\\\\\\\\“><a style style=“颜色:\\\\\\\\mt/“>博士Edmond Young,机械与工业工程系,多伦多大学米利卡半径生物材料和生物医学工程研究所,多伦多大学刘新宇,机械工业工程系,多伦多大学现在开放注册!<strong>截止注册时间将为午夜<strong>4月23日,2019 < /强>摘要提交截止日期为4月15日,2019!<b><p><p>The meeting will be hold in the<strong>george ignatieff theatre</strong>located at:<p>15 devonshire pl,多伦多,在M5S 2c8上,可以在以下网址找到关于场地方向的更多信息:<p><p><a href=“http://www.trinity.utoronto.ca/visit/bookings/git/audience.html”>http://www.trinity.utoronto.ca/visit/bookings/git/audience.html=<a><p>any questions about the event,请联系<a href=“mailto:dan.voicu@utoronto.ca”>dan.voicu@utoronto.ca</a><p><div class=“lightsocial_container”><a class=“lightsocial_a”href=“http://digg.com/submit”?url=http%3a%2f%2fbloblog.rsc.org%2flc%2f2019%2f03%2f12%2f2019-2f2019-联合-安大略省-on-a-chip-and-toep-syconpa%2f&title=2019+联合+安大略省-on-a-chip+and+toep+sysymba“><img class=“Lightsocial\u img”src=“http://blog.rsc.org/lc/wp-conte/plugins/lig-社会/digg.png.png”alt=“digg this”title=“digg本届”/>/>/>/>>>;<a class=“Light社交社交_a”a”a 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