D.Fogget al.have discovered a powerful means to observe the behaviour of Grubbs metathesis catalysts.
TheUniversity of Ottawa researcherstagged first- and second-generation ruthenium catalysts with a13C label at the alkylidene site using straightforward synthesis routes.This isotopic enrichment allowed13C NMR spectroscopy to serve as a sensitive probe for the amine-initiated decomposition pathway.
A surprising preference for nucleophilic attack by phosphine was clearly revealed in the13C NMR spectrum. This demonstrates the diagnostic utility of13C-enriched complexes relative to both their unlabelled and deuterium-labelled analogues.
This article is featured amongst many other excellent contributions in the latestCatalysis 新利手机客户端Science & Technologythemed issue,Mechanistic Studies in Catalysis.
Take a look at the original article online now!
Isotopic Probes for Ruthenium-Catalyzed Olefin Metathesis
Justin A.M.Lummiss,Adrian G.G.Botti,and Deryn E.Fogg*
Catal.Sci.Technol.2014,Advance Article,DOI:10.1039/C4CY01118J
Jenna Flogeras obtained her B.Sc.and M.Sc.in 新利手机客户端Chemistry from the University of New Brunswick (Fredericton), Canada.She is currently a Ph.D.student at Memorial University in Newfoundland,where she studies aluminum-based catalysts under the supervision of Dr.Francesca Kerton.
