We are delighted to share with you the top 30 most downloaded articles inToxicology Researchfrom January-December 2016. All of these papers arefree to accessfor the next two weeks with a free publishing personal account –register here.
Comment on “Promising blood-derived biomarkers for estimation of the postmortem interval” by I. Costa, F. Carvalho, T. Magalhães, P. G. de Pinho, R. Silvestre & R. J. Dinis-Oliveira. (Toxicol. Res., 2015, 4, 1443–1452)
Joris Meurs and Katarzyna M. Szykuła
Toxicol. Res.，2016年，5, 714-715
DOI: 10.1039/C5TX00397K
Mycotoxins: cytotoxicity and biotransformation in animal cells
Jikai Wen, Peiqiang Mu and Yiqun Deng
Toxicol. Res.，2016年，5, 377-387
DOI: 10.1039 / C5TX00293A
Key mechanisms involved in ionizing radiation-induced systemic effects. A current review
Ifigeneia V. Mavragani, Danae A. Laskaratou, Benjamin Frey, Serge M. Candéias, Udo S. Gaipl, Katalin Lumniczky and Alexandros G. Georgakilas
Toxicol. Res.，2016年，5, 12-33
DOI：10.1039 / C5TX0022B
Characterization of a functional C3A liver spheroid model
Harriet Gaskell, Parveen Sharma, Helen E. Colley, Craig Murdoch, Dominic P. Williams and Steven D. Webb
Toxicol. Res.，2016年，5，1053-1065
DOI: 10.1039/C6TX00101G
Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
Emma Wincent, Florane Le Bihanic and Kristian Dreij
Toxicol. Res.，2016年，5, 788-799
DOI: 10.1039/C6TX00004E
Improving the prediction of organism-level toxicity through integration of chemical, protein target and cytotoxicity qHTS data
Chad H. G. Allen, Alexios Koutsoukas, Isidro Cortés-Ciriano, Daniel S. Murrell, Thérèse E. Malliavin, Robert C. Glen and Andreas Bender
Toxicol. Res.，2016年，5, 883-894
DOI：10.1039 / C5TX00406C
Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids
Katarzyna Wojdyla, Krzysztof Wrzesinski, James Williamson, Stephen J. Fey and Adelina Rogowska-Wrzesinska
Toxicol. Res.，2016年，5，905-920.
DOI: 10.1039/C5TX00469A
1H NMR-based urine metabolomics for the evaluation of kidney injury in Wistar rats by 3-MCPD
Jian Ji, Lijuan Zhang, Hongxia Zhang, Chao Sun, Jiadi Sun, Hui Jiang, Mandour H. Abdalhai, YinZhi Zhang and Xiulan Sun
Toxicol. Res.，2016年，5, 689-696
DOI: 10.1039/C5TX00399G
三氯乙烯的表观遗传毒性：单分子透视
Yi Cui, Samrat Roy Choudhury and Joseph Irudayaraj
Toxicol. Res.，2016年，5, 641-650
DOI: 10.1039/C5TX00454C
Genome-wide transcriptional analysis of silica nanoparticle-induced toxicity in zebrafish embryos
Hejing Hu, Qiuling Li, Lizhen Jiang, Yang Zou, Junchao Duan and Zhiwei Sun
Toxicol. Res.，2016年，5, 609-620
DOI: 10.1039/C5TX00383K
Silver nanoparticles induced oxidative and endoplasmic reticulum stresses in mouse tissues: implications for the development of acute toxicity after intravenous administration
瑞辰，林兆，茹白，英柳，萍汉，志塘徐，冯辰，赫曼自动化，鼎鑫龙和珍贵陈
Toxicol. Res.，2016年，5, 602-608
DOI：10.1039 / C5TX00464K
化学类别方法的鲈鱼钾通道堵塞的硅预测
Chen Zhang, Yuan Zhou, Shikai Gu, Zengrui Wu, Wenjie Wu, Changming Liu, Kaidong Wang, Guixia Liu, Weihua Li, Philip W. Lee and Yun Tang
Toxicol. Res.，2016年，5, 570-582
DOI: 10.1039/C5TX00294J
Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies
Iness R. Benmessaoud, Anne-Laure Mahul-Mellier, Endre Horváth, Bohumil Maco, Massimo Spina, Hilal A. Lashuel and Làszló Forró
Toxicol. Res.，2016年，5, 407-419
DOI: 10.1039/C5TX00303B
Modeling the toxicity of chemical pesticides in multiple test species using local and global QSTR approaches
Nikita Basant, Shikha Gupta and Kunwar P. Singh
Toxicol. Res.，2016年，5, 340-353
DOI: 10.1039/C5TX00321K
Cytotoxic and sublethal effects of silver nanoparticles on tendon-derived stem cells – implications for tendon engineering
Tik Shing Cheung, Pui Man Lau, Haifei Lu, Ho Pui Ho, Pauline Po Yee Lui and Siu Kai Kong
Toxicol. Res.，2016年，5，318-330
DOI: 10.1039/C5TX00349K
低剂量苯并（A）芘暴露对人细胞的累积代谢效应
Qian Ba, Chao Huang, Yijing Fu, Junyang Li, Jingquan Li, Ruiai Chu, Xudong Jia and Hui Wang
Toxicol. Res.，2016年，5, 107-115
DOI: 10.1039/C5TX00378D
Evaluation of zinc-doped magnetite nanoparticle toxicity in the liver and kidney of mice after sub-chronic intragastric administration
山山朱，小龙徐，瑞荣，兵和薛王
Toxicol. Res.，2016年，5, 97-106
DOI: 10.1039/C5TX00292C
在暗条件下评价TiO2纳米结构的细胞内摄取和细胞毒性作用
Chieh-Wei Chen, Jing-Hong Huang, Tsung-Ching Lai, Yi-Hua Jan, Michael Hsiao, Chung-Hsuan Chen, Yeu-Kuang Hwu and Ru-Shi Liu
Toxicol. Res.，2016年，5, 303-311
DOI: 10.1039/C5TX00312A
静脉注射L-BMAA诱导大鼠模型，综合特征是肌营养的侧面硬化/帕金森 - 痴呆复合物的综合特征
Ke-Wei Tian, Hong Jiang, Bei-Bei Wang, Fan Zhang and Shu Han
Toxicol. Res.，2016年，579-96
DOI: 10.1039/C5TX00272A
基于雄性大鼠代谢组织的肾毒性血浆生物标志物的筛选与验证
Yubo Li, Haoyue Deng, Liang Ju, Xiuxiu Zhang, Zhenzhu Zhang, Zhen Yang, Lei Wang, Zhiguo Hou and Yanjun Zhang
Toxicol. Res.，2016年，5, 259 - 267
DOI: 10.1039/C5TX00171D
用化学杂质和分散性定义的多壁碳纳米管胎肺成纤维细胞的毒性机制
Aparna Shinde and Candace S. J. Tsai
Toxicol. Res.，2016年，5, 248-258
DOI: 10.1039/C5TX00211G
Grape seed proanthocyanidin extract protects against perfluorooctanoic acid-induced hepatotoxicity by attenuating inflammatory response, oxidative stress and apoptosis in mice
Wenwen Liu, Changshui Xu, Xi Sun, Haibin Kuang, Xiaodong Kuang, Weiying Zou, Bei Yang, Lei Wu, Fangming Liu, Ting Zou and Dalei Zhang
Toxicol. Res.，2016年，5，224-234
DOI: 10.1039/C5TX00260E
Mouse hepatic neoplasm formation induced by trace level and low frequency exposure to diethylnitrosamine through β-catenin signaling pathway
Yu-Sang Li, Chang-Long Leng, Man-Tang Chen, Wei Kevin Zhang, Xiao-Jun Li, He-Bin Tang, Hong-Cai Shang and Li-Hua Zhu
Toxicol. Res.，2016年，5, 210-223
DOI: 10.1039/C5TX00317B
In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells
Gözde Kiliç, Carla Costa, Natalia Fernández-Bertólez, Eduardo Pásaro, João Paulo Teixeira, Blanca Laffon and Vanessa Valdiglesias
Toxicol. Res.，2016年，5，235-247
DOI: 10.1039/C5TX00206K
miR-122 plays an important role in ochratoxin A-induced hepatocyte apoptosis in vitro and in vivo
Liye Zhu, Tao Yu, Xiaozhe Qi, Bo Yang, Lei Shi, Haoshu Luo, Xiaoyun He, Kunlun Huang and Wentao Xu
Toxicol. Res.，2016年，5, 160-167
DOI: 10.1039/C5TX00104H
红葡萄酒多酚提取物通过相反的JAK / Stat和NRF2途径的调节有效地保护肠上皮细胞免受炎症
Carla Nunes, Natércia Teixeira, Diana Serra, Víctor Freitas, Leonor Almeida and João Laranjinha
Toxicol. Res.，2016年，5, 53-65
DOI: 10.1039/C5TX00214A
阿斯巴甜对人宫颈癌细胞的细胞毒性作用
Muthuraman Pandurangan，Gansukh Enkhtaivan和Doo Hwan Kim
Toxicol. Res.，2016年，5, 45-52
DOI: 10.1039/C5TX00269A
在麻省理工学院mid-respiratory链抑制的影响ochondrial function in vitro and in vivo
Ashley J. Broom, Jeffrey Ambroso, Gino Brunori, Angie K. Burns, James R. Armitage, Ian Francis, Mitul Gandhi, Richard A. Peterson, Timothy W. Gant, Alan R. Boobis and Jonathan J. Lyon
Toxicol. Res.，2016年，5, 136-150
DOI: 10.1039/C5TX00197H
Mechanistic understanding of molecular initiating events (MIEs) using NMR spectroscopy
Paul N. Sanderson, Wendy Simpson, Richard Cubberley, Maja Aleksic, Stephen Gutsell and Paul J. Russell
Toxicol. Res.，2016年，5, 34-44
DOI：10.1039 / C5TX00246J
Evaluation of CdTe/CdS/ZnS core/shell/shell quantum dot toxicity on three-dimensional spheroid cultures
Mehriban Ulusoy, Antonina Lavrentieva, Johanna-Gabriela Walter, Franziska Sambale, Mark Green, Frank Stahl and Thomas Scheper
Toxicol. Res.，2016年，5, 126-135
DOI: 10.1039/C5TX00236B
We hope you enjoy reading thetop 30 most accessed articles of 2016and wish you all the best for 2017.
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